Second Nature Care Blog

Can you Smell Parkinson's? - I.V. Ozone, Good Gut

[fa icon="calendar'] Apr 9, 2019 11:09:06 PM / by Winter Ninivaggi


Sniffing out Parkinson's. In the early 1980's, nurse Joy Milne began to notice a distinct musky odor on her husband. A few years later her husband was diagnosed with Parkinson's disease, but Milne didn't connect the two disparate events until she later joined a Parkinson's charity and started meeting other sufferers. It was here she began to notice every person with Parkinson's disease could be identified by this same unusual and distinct odor.

In the early 1980's nurse Joy Milne noticed a musky odor on her husband and a few years later he was diagnosed with Parkinson's but did not connect the two until after speaking with out sufferers. In 2012 Milne approached a neuroscientist giving a talk on Parkinson's and claimed to be able to smell the disease. The scientist decided to test her claim.  Since then, a team of researchers has been working to isolate and identify the compounds Milne associated with Parkinson's. 

After years of work these researchers claim success and suggest this discovery could lead to an early detection test for the disease.

Sebum is an oily substance secreted by the skin. Research has shown that Parkinson's patients tend to excessively produce sebum and it was hypothesized that molecules in the sebum were causing the scent. Researchers zoomed in on samples of sebum from Parkinson's patients finding a handful of specific volatile molecular biomarkers were unique to the sebum of Parkinson's patients. 

It has been suggested that by tracking the levels of these specific molecules in sebum samples the disease can be identified in a variety of different stages. "Now we have proved the molecular basis for the unique odor associated with Parkinson's we want to develop this into a test," says Perdita Barran, a scientist working on the project from the University of Manchester. "This could have a huge impact not only for earlier and conclusive diagnosis but also help patients monitor the effect of therapy. We hope to apply this to at risk patient groups to see if we can diagnose pre-motor symptoms, and assist with potential early treatment."  (Haridy, 2019)

For the patient, loss of smell is another clue to developing Parkinson's. 

Parkinson's requires dopamine transporter or DAT imaging for a definitive diagnosis.  Loss of smell might be the first clinical sign of a disease years before it becomes more degenerative.  If loss of smell is documented and imaging is reflexively ordered then treatments can be used earlier before there is severe pathological changes in the brain.  Early diagnosis equals better prognosis.  

Treatment begins in the gut. We remove all gluten, most grains and dairy out of the diet. Processed carbohydrates aggravate SIBO and don't allow leaky gut mucosa to heal properly. High-protein foods block the absorption of the main Parkinson's medications - Levadopa or L-dopa which affects their efficacy. You are also tested for Herpes 6 and elevated heavy metals with an eye on mercury. The golden triangle in Parkinson's is poor gut function, high viral loads, previous exposure to pesticides and elevated mercury.

We use gold standard heavy metal testing with provocative challenge with EDTA and DMSA. We offer ozone chelation, a superb treatment modality combination that saves the patient time and money. Normal chelation takes between 30-40 treatments, but Ozone Chelation turbo charges the process and can accomplish the goal in 12 sessions.

Because of poor gut function I strongly recommend I.V. therapies. Ozone chelation and I.V. glutathione both improve function while we are healing the gut with L-glutamine, fish oils, NAC, turmeric, probiotics, gelatin, phosphatidyl choline and resveratrol.

Book Consult

Parkinson's Begins in the Gut

Cognitive Decline After Parkinson's

Parkinson's and the Gut Microbiome



Haridy, R. (2019, March 21). Smell of Parkinson's finally identified, early detection test on the way. Retrieved from

Winter Ninivaggi

Written by Winter Ninivaggi

Isadora Guggenheim, ND, RN, MS, CNS LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963