The popular Ketogenic diet anti-seizure effects.
The Keto diet was originally intended to treat children with severe epilepsy and developed over a century ago. Although it worked, it has never been unclear exactly how. A recent study conducted by UCLA suggests the diet can elevate levels of specific gut bacteria that affect certain neurotransmitters to reduce the risk of seizures.In 1921 the Ketogenic diet was developed after researchers discovered that fasting reduced the frequency of seizures in patients, then discovering that high-fat/low-carb diet yielded the same results. When modern anticonvulsant drugs were created, the keto diet as a treatment for epilepsy became outdated only re-emerging as a weight-loss fad due to its similarity to the Atkins Diet.
Recently, Keto Diets have been used for a variety of metabolic and psychiatric disorders as well. The ketogenic diet has also been known to be beneficial for patients with colon cancer.
The researchers found that the ketogenic diet reduces the amount of seizures and significantly alters gut microbiota in less than 4 days. It was found that levels of Akkermansia muciniphila and Parabacteroides (gut-bacteria) were elevated by the diet. These two particular bacteria work to generate seizure reducing effects. "They reduce gut and blood levels of gamma-glutamylated amino acids this subsequently elevated hippocampal GABA/glutamate levels, which reduced the amount of spontaneous seizures in the mouse models."
This study gives a complete description of exactly how the keto diet alters the gut bacteria resulting in direct action to the brain.
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Haridy, R. (2018, May 25). Gut bacteria mechanism behind the anti-seizure effects of ketogenic diet uncovered. Retrieved from https://newatlas.com/ketogenic-diet-epilepsy-gut-bacteria/54767/?utm_medium=email&utm_campaign=2018-05-25 184650 USA Daily Basic 2018-05-25 184918 All-terrain teardrops mil-spec boxes and camping trailers from Overland Expo West&utm_content=2018-05-25 184650 USA Daily Basic 2018-05-25 184918 All-terrain teardrops mil-spec boxes and camping trailers from Overland Expo West CID_7c684fff774cdbe6c09721bb7bf01dcf&utm_source=Campaign Monitor&utm_term=Gut bacteria mechanism behind the anti-seizure effects of ketogenic diet uncovered