Sometimes eating the right food still renders you over weight. A research team at the University of Montreal Hospital Research Centre (CRCHUM) has discovered that the ABHD6 enzyme in certain brain neurons plays a key role in controlling body weight.
You have eaten the right foods, exercised and tried all the diet plans , but no matter how hard you try or what you lose it always comes back. The team suggests that this may be due to an enzyme in the brain. The alpha/beta hydrolase domain-6 enzyme or ABHD6. Using mice as test subjects the researchers tested the effects of blocking this enzyme. It showed that when this enzyme is blocked in certain neurons of the mouse hypothalamus it becomes impossible to lose weight, even if they adhere to a strict mouse diet plan.
They discovered that when challenged, the mice who had the ABHD6 enzyme blocked were unable to adapt, no longer consume food after a fast, could not maintain body temperature during exposure to cold, were more susceptible to become obese, and once they were obese they did not lose weight even when strictly adhering to the diet.
Right now the enzyme disruption is only being studied in the hypothalamus, but more research will be conducted to see the effects of blocking the enzyme in the entire brain.
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