Oral Immunotherapy for Tree Nut Allergy in Children

Tree nut allergy is the most common food allergy among adults and children.

Oral immunotherapy is a technique used by doctors and allergists to retrain the immune system to tolerate food proteins and allergens through regular eating of small amounts of the food.

Allergy to tree nuts can cause very serious reactions (anaphylaxis) and could even be potentially fatal and is generally life-long. Tree nuts include, but are not limited to, walnut, almond, hazelnut, cashew, pistachio and Brazil nuts.

A recent and ongoing study found that long-term walnut oral immunotherapy induces clinically relevant treatment response in children with tree nut allergy. Significant clinical, immunologic, and serologic cross reactivity has been described among tree nut families. Multi–tree nut allergen sensitization is common with 46% reporting allergy to more than one tree nut.

Single allergen immunotherapy has demonstrated efficacy in desensitization to milk, egg and peanut allergies. The researchers evaluated a novel immunotherapeutic approach to tree nut allergy by using the walnut oral immunotherapy with the goal of inducing not only desensitization to walnuts but also the possibility of of cross-desensitization to a second tree nut.

"Dr. Scurlock reported on results from 9 of 14 children with allergy to walnuts and another test tree nut (pecans, cashews, hazelnuts, or pistachios) who received open-label walnut oral immunotherapy after completing 38 weeks of blinded, placebo-controlled treatment. Walnut and test tree nut desensitization oral food challenges were performed by 142 weeks. If they passed, the subjects stopped their treatment for four weeks. Next, they underwent another oral food challenge to determine if they continued to be sensitized or if they had developed sustained unresponsiveness."

Desensitization was observed in seven out of the nine subjects. After four weeks of the therapy four of the subjects who desensitized also demonstrated sustained unresponsiveness to both walnuts and test tree nuts and six of seven sustained unresponsiveness to just walnuts. While the walnut oral immunotherapy was generally well tolerated the researchers frequently observed oral allergy/ itching associated with dosing.

Further research will focus on strategies to optimize long-term sustainability/ tolerability of dosing and testing in a larger sample size. While the results are encouraging further research must be conducted in larger samples to further observe outcomes of the oral immunotherapy.

There is a special company that is able to make up custom formulas using samples of what you are allergic to like your dog dander and epithelium on a brush. The base formula works to lower histamine release, support the adrenals and reduces the production of cortisol. 

Like cures Like. These formulas work because the mechanism of action is based upon a thousand year old time-tested tenet of medicine.

So, whether you are allergic to animals, insects, airborne particles, grass and weeds, flowers, dust/mold, smoke or to proteins in caffeine, dairy, fruits, grains, seeds, gluten, nightshades, nuts, shellfish, sugar or vegetables - You are in luck because we can address your hypersensitivities to all of the above with allersode desensitization drops that are easy for all ages to take daily. We monitor your progress in the office for desensitization.  

Remedies are easy to store, safe and inexpensive. NO SHOTS. 

Call me if you have chronic allergies of any kind if you are sick and tired of being sick and tired.

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Children's Allergies