Ozone in Spain and Italy - What Did They Do and Why?

Many are wondering what they did in the clinical ozone studies in Spain and Italy that produced successful results recently. Let's review some details. 

•  Human physiology requires oxygen utilization 
• If we don't get oxygen - we die
• Decreased oxygen utilization is a physiological breakdown that links to decreased levels of NAD short for nicotinamide adenine dinucleotide 
• NAD is formed from either tryptophan or niacin

• Energy reactions in cells do not use oxygen directly. They rely on enzymes called dehydrogenases and these work through NAD
• NAD is created in the mitochondria in what is called electron transfer chain
• NAD is the oxidized form (oxygen added) of nicotinamide adenine dinucleotide
• To get to NAD - you must take NADH and oxidize it to get NAD 
• Oxidation means you are transferring electrons - this is fundamental to life force
• Once you have NAD - that means you can drive the cellular reactions to get oxygen into your cells
• Oxygen utilization means more NAD - high levels mean higher levels cellular oxidation 
• Healthy people have a ratio of NAD to NADH 700 to 1
• Did you know that DNA replication or all protein synthesis is 100% dependent on NAD?
• Our cellular repair systems are dependent on NAD so low levels can result in DNA and RNA mutations 
  
  From the World Federation of Ozone Therapy who did the trials in Spain and Italy
•  They found that ozone improved lung and peripheral tissue oxygenation and exchange of gases because red blood cells were able to produce more ATP (unit of energy) 
• Ozone modulates NrF2 which increases antioxidants in the cytoplasm, mitochondria and plasma - mainly glutathione peroxidase, glutathione reductase, NADPH and SOD 
• Induces the production of HO-1 a protective enzyme along with heat shock proteins, reduces pro-inflammatory chemicals or interleukins 
  What did they use in the trials? 
• 100 mL of blood and 100 mL of ozone gas at 30 mcgr/mL concentration.
  - In-hospital patients: each 12 hours application for minimum 14 days.Rectal insufflation if peripheral veins cannot be accessed 
• Auxiliary treatments 
• To help ozone effect, it is possible although not mandatory, the administration during the ozone treatment of:
  - Vitamin C: 3 gr each 12 hours, 6 hours after ozone administration. 1 gr each 12 hours is already standardize in Italy and Spain protocols for COVID19.
  - Glutathione: 600mg each 12 hours, 6 hours after ozone administration. This substance is administered because ozone effect is partially based on it and old patients may have a low blood glutathione level.

       Heparin must be used with I.V. Ozone to prevent blood coagulation. Since several patients have

       had difficulty with blood clots due to Covid-19 - heparin has been an assistive agent to prevent 

       blood clots and improve hypoxia (lack of oxygen).

Hope you are all doing well. I'll be writing about food poisoning and other interesting topics coming up. Tip of the day - microwave your dish sponges 3-5 times per day. Great vector for germs. Stay safe and stay sane. If you are having a mental health issue - call 

• 1-800-273-8255 (1-800-273-TALK) - National Suicide Prevention Lifeline
• 1-800-784-2433 (1-800-SUICIDE) - National Hopeline Network
• 1-866-488-7386 (1-866-4.U.TREVOR aimed at gay and questioning youth)
  
  See you on the other side of this crisis. Your ozone expert.Dr. Isadora Guggenheim ND, FNP, RN, CNS, MS, LMT