Your health starts in your Gut. And so does Parkinson's.
A bacterium in the gut microbiome could predict the possibility of developing Parkinson's disease. The presence of Corynebacterium in the gut microbiome of people with two G alleles at the rs356219 single nucleotide polymorphism locus of the alpha synuclein gene was associated with 100% probability of having Parkinson's according to a study conducted by the NeuroGenetics Research Consortium.
The two G alleles at the rs356219 is the strongest genetic risk factor known to date but, not necessarily strong enough to cause the disease on its own. It is possible that presence of the Corynebacterium is what is the triggering factor. Medical literature is full of clues that Parkinson's could be set off by an issue in the gastrointestinal tract. Colonic inflammation, alpha-synuclein pathology in the gut, and dysbiosis of the gut microbiome in PD are among the many clues.
"Corynebacterium was more abundant in GA subjects with PD than GA subjects without PD, but it was by far the most abundant in GG subjects, and every person who had the GG genotype and gut Corynebacterium also had PD."
Corynebacterium are gram-positive, aerobic bacilli commonly found on the skin. Some members of the genus are opportunistic pathogens. It’s not clear how they get incorporated into the gut microbiome, or if they can be wiped out selectively in the gut with antibiotics or probiotics.
We understand that Parkinson's is in the gut and we begin treatment in the gut. We remove all gluten, most grains and dairy out of the diet. Processed carbohydrates aggravate SIBO and don't allow leaky gut mucosa to heal properly. High-protein foods block the absorption of the main Parkinson's medications - Levadopa or L-dopa which affects their efficacy. I also test for Herpes 6 and elevated heavy metals with an eye on mercury. The golden triangle in Parkinson's is poor gut function, high viral loads, previous exposure to pesticides and elevated mercury.
Because of poor gut function, I strongly recommend I.V. therapies. Ozone chelation and I.V. glutathione both improve function while we are healing the gut with L-glutamine, fish oils, NAC, turmeric, probiotics, gelatin, phosphatidyl choline/serine and resveratrol.
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Neurological Conditions: MS, ALS, Dementia, Parkinson's We create your unique formula using the advanced I.V. Ozone and specialized medicines from Germany.
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Reference:
Wallen Z et al. ANA 2017 abstract number S268
The study was led by Zachary Wallen, a PhD candidate in Dr. Payami’s lab, and presented by him at the annual meeting of the American Neurological Association.