Stopping cancer's attacks on the immune system.
Cancer uses a variety of dirty tricks to ensure its survival and spread in the body. Researchers at Rush University and the University of California, San Diego have found a way to stop one if the plots in its tracks and preventing tumors from recruiting immune cells to help them grow and metastasize.
Myeloid cells, a type of white blood cell, patrol the body in search of pathogens. There are two types of them, the M1 Macrophage has been found to suppress tumor growth while the M2 Macrophage does the exact opposite by fighting off helpful T Calls and helping the cancer to grow and spread.
The study uncovered a vital clue to what makes myeloid cells M1 or M2. The key is a protein called CD11b found on the surface of myeloid cells. When CD11b activity increases as do the number of M1 cells, inversely when activity is low more M2 cells develop. Cancer tumors take advantage of this by actively suppressing the protein to make more M2 cells and ultimately boost their growth.
After the discovery of this mechanism, researchers experimented to see if CD11b could be a potential target for cancer treatment and engineered mice that completely lacked the protein and transplanted tumors into them, finding that the tumors grew much bigger than control-group mice.
With that mechanism uncovered, the researchers then experimented to see if CD11b could be a potential target for cancer treatment. They engineered mice that completely lacked the protein then transplanted tumors into them, and found that those tumors grew much bigger than tumors in control-group mice."Next, the team tried the inverse. They gave normal mice a molecule called Leukadherin-1 (LA-1), which boosts the function of CD11b, and found that tumors shrank significantly. And finally, to make doubly sure that this protein was the right target, they engineered a mouse that had CD11b active all the time, instead of just sporadically like normal mice. Their tumors also shrank drastically." (Irving, 2019)
These results may be the door to a promising new immunotherapy technique.
Ozone therapies can be valuable adjunctive cancer care therapy and can be done in conjunction with chemo and radiation. Ozone therapy increases oxygen utilization allowing oxygen into every cell. Cancer hates oxygen and ozone kills cancer cells. Ozone has been proven to reduce ROS or reactive oxygen species which cause the formation of free radicals.
Chemotherapy and radiation cause oxidative stress and a host of side effects. Several cases published in the German literature show that ozone therapy combined with standard oncology produced positive effects, decreased side effects and created less resistance to chemotherapeutic drugs.
While chemo and radiation might be effective in individual cases it is not necessarily safe or affordable. Two out of every 5 patients who follow standard of care for cancer get diagnosed with a secondary cancer that is more lethal. So you survive the first cancer only to face a more virulent one.
Ozone therapy is safe, effective and affordable. Ozone does not cause cancer.
Irving, M. (2019, January 07). Breakthrough study stops cancer hijacking immune cells. Retrieved from https://newatlas.com/cancer-hijack-immune-system-treatment/57900/