Researchers discovered prevention properties of protein in fatty liver disease.
Non- Alcoholic Fatty liver disease (NAFLD) generally leads to chronic inflammation (non–alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. The researchers revealed that the CPEB4 protein has the power to prevent fatty liver disease.
A number of studies have linked variants of the CPEB4 gene with the impairment of fat metabolism. The study found that this protein is necessary in driving liver stress response.Specifically, under stress, caused by uncontrolled ingestion of fats for example, the endoplasmic reticulum – a cell organelle associated with protein synthesis and folding and lipid metabolism – stops its activity in order to reestablish cell equilibrium. This “clean–up” mechanism is orchestrated by CPEB4 and varies in function of the time of day – being more active in humans during the day (when the liver has most work) and dropping off at night. Without CPEB4, the endoplasmic reticulum is unable to activate the stress response, thus causing hepatocytes to accumulate the lipids produced by the fatty liver.
Understanding the function of CPEB4 could render it a useful predictive marker for those with variants of the protein and thus serving to prevent fatty liver.
NAFLD is associated with obesity as well so maintaining healthy daily exercise habits are important.
Fatty liver disease can leave you feeling fatigued, bloated, weak, constipated and nauseous. You may be suffering from pain in the upper right area of your abdomen or even experience dizziness and confusion.
If you are concerned about the possibility of having fatty liver disease give us a call. We successfully have reversed the effects of fatty liver disease at Second Nature Care. It all starts with major diet changes. Only limited healthy fats and absolutely no soda. We also offer an array of supplements and treatments that are individualized. Our I.V. Glutathione, I.V. Alpha Lipoic Acid and Ozone treatments are a great treatment choice. All I.V. therapies are MD ordered and RN/NP administered in NYS.
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