Stem cells to insulin producers.
Diabetes is a result of the body's inability to keep blood sugar levels in check which is something handled by insulin. Research has traced this back to faulty beta cells in the pancreas failing to produce this hormone. Scientists have now made a promising breakthrough in this area describing a novel technology that converts stem cells into insulin-secreting beta cells by harnessing an often over-looked step in maturation.
Patients suffering with Type 1 diabetes have to keep tabs on sugar levels in the blood, manually monitoring blood-sugar levels and injecting insulin as needed. Pancreas transplants are also an option and hard to obtain. Researchers at the University of California San Diego report of the 1.5 million sufferers in the U.S. alone, only about 1,000 receive transplants each year.
Among scientists leading the way for developing new sources of treatment for diabetes is Matthias Hebrok, director of the Diabetes Center at UCSF. His team is seeking to grow beta cells that can be transplanted into patients using stem cells as their starting point.
They believe they have "cracked the code". The scientists recreated the natural process whereby beta cells in the pancreas form clusters called the islets of Langerhans. They began by manually sorting beta cells into clusters and transplanting them into healthy mice and then watch as the cells matured within days and began producing insulin in response to glucose cells.
Similar research at Washington University in St Louis was conducted recently where scientists made a breakthrough in producing mature beta cells that secreted insulin in a matter of days. They were able to achieve this by treating the cells with various growth factors along the way.
"We are separating cells at the immature beta cell stage and recombining desired cell populations, such as cells that are positive for insulin," Hebrok explains to New Atlas. "Re-aggregation not only generates beta cells, but also other endocrine islet cell types, like alpha and delta cells. Having other islet cells present likely will be beneficial in the long run as this is closer to the normal cellular organization found in native human islets." (Lavars, 2019)
Patients with type 1 diabetes see an association between higher physical activity and a larger hippocampus and it appears robust to chronic hyperglycemia and insulin sensitivity, a recent study found. The study was conducted using participants who were middle aged with a mean age of 50 using neuroimaging and self-reported physical activity data.
Get out and get active! Exercise shows benefits to brain health in many different ways, such as depression and Alzheimer's. The hippocampus size and physical activity relationship was only found to be significant in patients who had type 1 diabetes.
I recommend Xymogen's CinnDromX capsules and OptiMetabolix fast-acting shakes to stabilize blood sugar levels. Daily exercise is a must for everyone to stimulate the insulin receptors and improve the intestinal microbiome.
One of the best treatments is ozone chelation. Both therapies have been shown to reverse Type II diabetes. Chelation removes heavy metals that cause cardiovascular disease and free radical activity. Ozone kills pathogens that damage organ systems including the pancreas. The National Institutes of Health TACT Trial to Assess Chelation Therapy showed that 37% of patients with diabetes out of a total of 1700 patients had a 41% reduction in cardiac events, 52% drop in recurrent myocardial infarctions and 43% reduction of deaths. Chelation should become mainstream treatment for Type II diabetes. All Ozone therapies are MD ordered and supervised in NYS.
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Lavars, N. (2019, February 12). Clustered stem cells become working insulin producers in potential cure for diabetes. Retrieved from https://newatlas.com/stem-cells-insulin-producers-diabetes-cure/58437/