We're not doing the Ice Water Challenge in this weather but, you can still test your ALS knowledge!
Take this quiz and see how much you know about ALS and find out how we treat ALS naturally.
1. True or False. The C9orf72 mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS).
A. True
B. False
2. The C9orf72 mutation affects up to approximately _____ of cases of familial cases of ALS and approximately _____ of sporadic cases.
A. 20%; 50%
B. 30%; 30%
C. 50%; 20%
3. True or False. The C9orf72 repeat expansion mutation can include frontotemporal dementia.
A. True
B. False
4. According to research findings, the C9orf72 repeat expansion mutation carries negative prognostic characteristics in ALS, primarily for __________ patients with spinal-onset disease.
A. Male
B. Female
5. True or False. Male spinal-onset C9orf72 expanded cases of ALS were also more likely to have experienced a shorter diagnostic delay.
A. True
B. False
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Answers:
1. A. True - “The C9orf72 mutation represents the most common genetic cause of ALS,” according to information cited in a literature review article published online in Neurology Reviews. The article reviewed a report originally published in the Journal of Neurology, Neurosurgery and Psychiatry.
2. C. 50%; 20% - The C9orf72 mutation “affects up to 50% of familial cases and 20% of sporadic cases” of ALS, according to a literature review article published online in Neurology Reviews, which discussed a report originally published in the Journal of Neurology, Neurosurgery and Psychiatry.
3. A. True - ALS that is based in C9orf72 repeat expansion mutation “is associated with a distinctive clinical phenotype that sometimes includes frontotemporal dementia,” according to a literature review article published online in Neurology Reviews, which discussed a report originally published in the Journal of Neurology, Neurosurgery and Psychiatry.
4. A. Male - “Researchers have shown that the negative prognostic characteristics of the C9orf72 repeat expansion in [ALS] apply primarily to males with spinal-onset disease,” according to a literature review article published online in Neurology Reviews, which discussed a report originally published in the Journal of Neurology, Neurosurgery and Psychiatry.
5. A. True - “‘Male spinal-onset C9orf72 expanded cases [of ALS] were also more likely to have experienced a shorter diagnostic delay, suggesting rapidly progressing disease,’” according to a literature review article published online in Neurology Reviews, which discussed a report originally published in the Journal of Neurology, Neurosurgery and Psychiatry.
For complete information, see:
“Genetic Insights Refine Prognostic Information in ALS.
