This is the most common viral sexually transmitted disease in the United States, with women accounting for 67% of infections.
Ano-genital warts are caused by Human Papilloma Viruses (HPVs) which are small, nonenveloped, double stranded DNA viruses. In a condyloma, viral replication is associated with excessive proliferation of all of the epidermal layers except the basal layer.
An effective immune system is important in the resolution of HPV infection. HPV infection occurs more frequently and is more severe in patients with primary and secondary immunodeficiencies. Severe and frequent HPV disease is seen in HIV/AIDS patients. Compared with HIV- seronegative subjects, AIDS patients have an increased risk for malignant transformation.
Xymogen's Immunotix 500, Vitamin D3 (soy-free), Viragraphis and IgG 26DF
Genital HPV infections are classified according to their risk of causing cervical cancer. Low risk HPV types 6 and 11 cause 90% of anogenital warts. These warts affect approximately 1% of the population and an annual incidence of 6 million has been estimated in the United States. This makes anogenital warts the most commonly acquired viral sexually transmitted disease in the United States. It is estimated that at least three quarters of the population may have been infected in their lifetime. Prevalence of condyloma is higher in patients who are HIV positive or who have other forms of STD.
Evidence that anogenital warts are sexually transmitted includes the observation that the age of onset is similar to that of other STDs and that genital warts develops in about two-thirds of sexual contacts of patients with anogenital warts. In addition, patients with anogenital warts often have other concomitant STDs or a history of STD's. Vaginal-penile intercourse is the most common route of transmission. However, HPV can be transmitted among "virgins" via non penetrative sexual skin to skin contacts.
Genital warts develop between three to four months but the range could vary from three weeks to eight months, and infection is usually transient and cleared within two years. Persistent infections in the setting of other clinical risk factors (HIV) are associated with the development of squamous cell carcinoma.
Risk Factors :
- Vaginal/penile intercourse or anal/penile intercourse, digital/anal, oral/anal and digital/vagina
- High number of lifetime or sexual partners in the past year
- Being single, lower socioeconomic status, lower educational level, non-hispanic black race and immunosuppression
In women, the vulva is the most common area affected. The vagina, anus, cervix and urethra can also be affected. About three quarters of patients with anogenital warts are asymptomatic. However, women may complain of pruritus, bleeding, burning, tenderness, vaginal discharge or pain. They may also experience growth or swelling in the perineum/perianal area.
Anogenital warts are flesh to gray colored, hyperkeratotic, exophytic papules, either sessile on the skin or, more frequently, attached by a short, broad peduncle. Lesions could be smooth, pearly papules to more jagged acuminate growths. They vary in size from less than a millimeter in diameter to several square centimeters when they merge into plaques. Condyloma can occasionally form large exophytic masses that can interfere with intercourse, vaginal delivery, or defecation. Large lesions are commonly seen among HIV positive women.
The diagnosis of Human Papilloma Virus is typically visual and made during a physical examination. The extent of involvement should be documented by examination, speculum exam, colposcopy, or an oscopy as required. Acetic acid to the lesion turns the lesion white in appearance, which facilitates better identification. Typically, lesions are shiny white patches with poorly defined borders that may have an irregular surface containing characteristic capillary loops.
Let's discuss lifestyle habits, how to improve your immune system and what treatment modalities would be beneficial for your condition. I.V. Ozone, I.V. immune botanicals, oral homeopathy, diet, ozone insufflation and ozone cream are just a few ways HPV can be addressed locally and systemically. All Ozone therapies are MD ordered in NYS.
Written by Isadora Guggenheim
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We discuss lifestyle habits, increasing your Vitamin A and D, bolstering your immune system, taking natural anti-virals, improving your diet and doing ozone therapies. I.V. ozone MAH, rectal insufflation and topical ozone gas on the condylomas as well as ozone cream applied to lesions directly are accepted treatment methods.