Second Nature Care Blog

The Pathway to Heart Health

[fa icon="calendar'] Sep 23, 2017 5:00:00 AM / by Winter Ninivaggi

New evidence is reducing the risk of cardiovascular events.


New evidence that targeting an inflammatory pathway can reduce heart attacks and stroke independent of lipids has been released. Canakinumab (Ilaris) , a prescription drug reduced such events by 15% as compared with a placebo.  But, there is a catch! Not only does the immunotherapy drug carry a hefty price tag, but it was associated with an increased risk of fatal infections.

Canakinumab is a human monoclonal antibody that targets interleukin-1 beta innate immunity pathway and it is approved currently as an orphan drug for treatment of two rare pediatric conditions. It is administered monthly and is priced at about $200,000 per year!

"In the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS), 150 mg of canakinumab every 3 months reduced high-sensitivity C-reactive protein (hs-CRP) levels by an average of 37% compared with placebo and achieved a 15% reduction in cardiovascular events -- mostly MIs -- compared with placebo, Paul Ridker, MD, reported here at the European Society of Cardiology 2017 congress."

"He noted that, although there was no cardiovascular mortality benefit, there was 30% reduction in need for bypass surgery, angioplasty, and heart failure -- all of which means a significant improvement in quality of life. And treatment was also associated with a reduction in gout, rheumatoid arthritis, and osteoarthritis, he said. However, the treatment had no effect on lipids, which suggests that the benefit was all attributable to the anti-inflammatory activity. But Ridker added that the inflammatory hypothesis in no way competes with the lipid hypothesis. "I think statins are the miracle drugs of the century, and all of these patients [in CANTOS] were on aggressive statin therapy.""

If you are looking for a way to be heart healthy without the excessive price tag and the dangerous side effects - My top picks are:

Order Xymogen

Xymogen's Cardio Essentials, CoQmax Ubiquinol or CoQmax 100 ME, L-Carnitine, Magnesium, Methyl Protect and ATP Ignite. For lower blood pressure - AngiNox and N.O.max ER. Need to get your lipids back in line - NiaVasc 750 in conjunction with an overhauled diet and exercise. CoQenzyme 10 is an antioxidant that is in heart muscle and is critical for cardiac energy production. It increases ejection fraction in the left ventricle.  The Q-SYMBIO study showed that  CoQ10 reduced cardiovascular mortality and hospital stays in patients with heart failure.L-Carnitine shuttles fatty acids to the mitochondria. A meta-analysis of 3629 participants showed that L-Carnitine reduced all cause mortality by 27%, ventricular arrhythmias by 65% and angina by 40%.Magnesium, a critical co-factor, in several biochemical processes is the second most abundant intracellular cation next to potassium in the human body. Magnesium controls the heart's electrical and contractile functions of the heart. If you have high homocysteine then Methyl Protect is the nutraceutical of choice as it corrects your genetic differences to bring homocysteine levels down.ATP Ignite is a combination of electrolytes, trace minerals, B-vitamins, amino acids and antioxidants that support mitochondrial function to create usable energy. Taurine, an amino acid, protects the heart against stress hormones and high blood pressure. We offer it in injectable form. If you have high cholesterol and don't want to start taking statins then Cardiac Essentials NiaVasc 750 might be right for you.

I.V. Ozone therapy is a safe effective treatment and can be used with additional specialized injectable medicines for your case. Ozone chelation is fantastic for addressing elevated lead that causes cardiovascular disease.

We all need good cardiac support!

Book Consult

Anxiety and Heart Health

Are Statins Worth the Risk

Balance and Cardiovascular Disease

Peck, P. (2017, August 27). ESC: At Long Last, Inflammatory Hypothesis Confirmed in CVD by CANTOS. Retrieved August 28, 2017, from

Topics: Heart Health

Winter Ninivaggi

Written by Winter Ninivaggi

Isadora Guggenheim, ND, RN, MS, CNS LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963