Second Nature Care Blog

The Sexy Peptides - How to Turn on Your Libido

[fa icon="calendar'] Jun 26, 2020 3:39:38 PM / by Dr. Isadora Guggenheim

Do you feel that you have lost your sex drive? Is your partner complaining about your lack of interest? We offer amino acid peptides that can change your sex drive. This is a quality of life issue and many patients with resolved chronic disease patterns start to think about their sexual selves. 

Which Peptide works for libido? 

Bremelanotide PT-141 is now used to treat sexual dysfunction in men and women. Unlike other common medications, this peptide works in the central nervous system to increase libido and arousal by stimulating certain parts of the brain. 

WHO is this for?

The person who has trouble getting aroused, has trouble staying aroused or has difficulty orgasming. This peptide has been FDA approved for women and it is also effective in men with erections.


HOW does it work?

Our biggest sex organ is our brain and sexual function and performance starts in the brain. There are several neurochemical mediators which control the process, some increase libido and arousal while some decrease them.

Bremelanotide PT-141 causes excitatory behavior in the paraventricular nucleus of the brain by stimulating Melanocortinin receptors.

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Some patients will experience severe nausea shortly after injecting PT-141. This nausea does NOT happen with everyone and is quite patient dependent. Nausea can range anywhere from a 0 to a 10. • Some patients can experience flushing shortly after injection but subsides after a few minutes. • With consistent use, pigmentation of mucous membranes such as the gums, tongue, and labia can occur.


The Bremelanotide comes as a subcutaneous injectable as well as a nasal spray. The subcutaneous injectable is usually provided in a 2ml vial with a concentration of 10mg/ml and a total of 20mg/vial. This is usually enough for 20 doses for men and 10 doses for women.

OTHER CONSIDERATIONS FOR BREMELANOTIDE PT-141 Anecdotal experience has shown treatments such as anti-histamines can aid in mitigating the nausea side effects. Recently we have also experienced relief by using Alka-Seltzer Gold prior to injection. We also recommend not using more than twice weekly as patients can develop tachyphylaxis.

WHAT is a normal dose?  

Usually, men will start off with a subcutaneous dose of 1mg 2 hours before sexual activity. Women need a dose above 1.75mg in order to have statistically significant effects. Most women will start at a 2mg subcutaneous dose 2 hours before sexual activity.
We do not recommend combining with PDE5 inhibitors such as tadalafil during the first few doses for risk of priapism or prolonged erection. 

Quality of life issues matter. If you feel good and you want to connect with your partner - then this peptide might be right for you. Feel whole again. Improve your sexual health. 

Topics: Sexual Health

Isadora Guggenheim, ND, FNP, RN, MS, CNS, LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963