Second Nature Care Blog

Thyroid Function, The Liver, and MetS

[fa icon="calendar'] Mar 2, 2016 11:24:29 PM / by Isadora Guggenheim & Winter Ninivaggi


There are Clear associations between the the development of fatty liver disease and hypothyroidism. We're not talking about the baseball team, MetS refers to insulin resistance metabolic syndrome. There is a well established association between non-alcoholic fatty liver disease and insulin resistance/ metabolic syndrome.  In non-alcoholic fatty liver disease (NAFLD) insulin resistance fuels the chronic inflammation in the liver as opposed to a virus or toxicity. Consumption of high-fructose corn syrup is also associated with NAFLD. 

The thyroid and the liver play a large role in NAFLD. Thyroid hormones, T3 and T4, regulate the metabolic activity of hepatocytes and have a central role in hepatic growth, development, and function. Both of these hormones play a role in regulation of the permeability of vascular endothelial cells and are needed for bilirubin and bile secretion. Hepatic effects can be dramatic on thyroid dysfunction. With the promotion of thrombosis inflammation, vasoconstriction and oxidation, the liver can be converted into a generator of chronic disease.

Liver functioning tests can be altered by the effects of thyroid dysfunction. With thyroid hormone repletion liver function tests often revert back to normal levels. 

A number of drugs and treatments affect both the thyroid and the liver such as alcohol, propylthiouracil, amiodarone, mefloquin, carbamazepine, chemo therapy, hep C treatment, and radiation therapy. Diseases including: non-Hodgkins lymphoma, amyloidosis, Celiac disease, hemochromatosis, alcoholic liver disease, hepatitis C and primary biliary cirrhosis. 

Hypothyroidism enhances the damaging effects of bacterial endotoxins on the liver. A slowing of the MMC increases the risk for SIBO and a "leaky gut".

Both hypothyroidism and NAFLD can feature obesity, insulin resitence and dislipedemia. Thyroid dysfunction has the potential to contribute to the pathogenesis of fatty liver disease in susceptible individuals. 

Along with the changes in the gut flora and permeability a broader view of the effects of insulin resistance, thyroid, and liver can be seen. 

If you are concerned about the possibility of having fatty liver disease give us a call. We successfully have reversed the effects of fatty liver disease at Second Nature Care. It all starts with major diet changes. Only limited healthy fats and absolutely no soda. We also offer an array of supplements and treatments that are individualized. Our I.V. Glutathione is a great treatment choice.

We also offer Good Gut probiotics to regulate the gut flora and reverse the effects of a "leaky gut".. Your health starts with your gut. We work to reverse irregularities in the gut. 

 More About GOOD GUT





Topics: Chronic Illness and Disease, Body Health

Isadora Guggenheim, ND, FNP, RN, MS, CNS, LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963