Second Nature Care Blog

Gluten Free Summer

[fa icon="calendar'] May 18, 2022 12:54:00 PM / by Winter Ninivaggi posted in Autoimmune Disease

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Memorial Day weekend is right around the corner!

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More Than Meets the Eye - Rosacea and Autoimmune Disorders

[fa icon="calendar'] May 7, 2022 12:15:00 PM / by Winter Ninivaggi posted in Autoimmune Disease

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Hi, it's Winter! 

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IVERMECTIN - A Miracle Med for Parasitic Infections, Viruses and Inflammation

[fa icon="calendar'] Sep 29, 2021 8:00:00 AM / by Dr. Isadora Guggenheim posted in The Scoop on Poop, Autoimmune Disease, Ozone and Prolozone therapies, Chronic Illness and Disease

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Anti-Parasite, Anti-Viral and Anti-Inflammatory 

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DRY EYE More Susceptible to Covid

[fa icon="calendar'] Sep 9, 2021 8:12:04 PM / by Dr. Isadora Guggenheim posted in Autoimmune Disease, Ozone and Prolozone therapies, Corona Virus

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“An ozone-based ophthalmic gel could act as a barrier against the entry of the SARS CoV-2 virus, thus acting as a sort of mask for the eyes, to be used together with the mask that covers the nose and mouth”.

Click the link to the full article:

This is the idea proposed in a study entitled “COVID-19 Ocular Prophylaxis: The Potential Role of Ozonated-Oils in Liposome Eyedrop Gel”, published in the August issue of Translational Vision Science & Technology:

 The study was directed by Dr. Stanislao Rizzo, Full Professor of Ophthalmology at the Catholic University of the Sacred Heart, Rome campus, and Director of Ophthalmology of the Agostino Gemelli IRCCS University Hospital Foundation.

 “The ozone-based ophthalmic gels – said prof. Rizzo – are already used to relieve the symptoms of inflammatory eye diseases, including those of infectious origin. Our study suggests that they may also have a barrier effect against viruses that enter the eye or nasolacrimal system”.

“This is an in vitro study and the results will have to be confirmed by studies on animal models and humans,” said Rizzo.

 Learn about I.V. Therapies for dry eye, macular degeneration, cataracts and thyroid eye disease. We have treatment protocols. 

In a note, the IRCCS of the Gemelli Polyclinic explained that the SARS CoV-2 virus can also enter the body through the eyes.

In this regard, the study related what happened to a member of the US National Expert Panel on pneumonia, sent to Wuhan for inspection.

The man, who wore no eye protection, first developed conjunctivitis and then the classic Covid-19 pneumonia.

Other studies have shown that the virus can remain in the eye for several weeks after the acute phase of the disease.

 It was therefore discovered that the eyes are a target organ of SARS CoV-2, and that especially those suffering from dry eye syndrome are much more likely to be infected. Yes which human tissue requires the most oxygen? 

Answer: The Retina 

Aging begins in the eyes. That is why you must give your eyes special attention. Get regular eye exams yearly and especially after you have Covid or the vaccine. 

It was thus thought to enhance the barrier effect of tears against SARS CoV-2 by using a special ozone-based gel.

 In the note from the IRCCS of Gemelli it is specified that “ozone has long been used in medicine to disinfect and treat infectious diseases, given its ability to inactivate bacteria, viruses, fungi, yeasts and even protozoa. The antiviral activity of ozone occurs by damaging the viral capsid and altering replication through peroxidation”.

When asked how to spread ozone on the surface of the eye, prof. Rizzo replied that “ozone is very unstable, but to make it suitable for topical use, it can be stabilized by making it react with a monounsaturated fatty acid such as oleic acid to create the so-called ozonated oils, which retain the same properties gaseous ozone and are well tolerated by the tissues.”

“Ozonated oils – he added – are already used in the form of eye drops or ophthalmic gels to relieve the symptoms of inflammatory ocular diseases, including those of infectious origin; ozone also facilitates the healing of corneal damage by minimizing the risk of scarring and opacification of the cornea.”

“The objective of the study – explains prof. Rizzo – is to evaluate whether this eye gel can prevent SARS CoV-2 infection in the tissues of the eye, and also to evaluate whether, in patients with dry eye syndrome, ozone can help restore the integrity of the ocular surface, repairing and regenerating the conjunctival microvilli.”

The in vitro study provided positive results, demonstrating that the ozone-based ophthalmic gel inhibited viral replication and the entry of the virus into the cells on the surface of the eye (corneal and conjunctival).

 It has also been shown that ozone eye gel restores cell regeneration and controls inflammation in dry eye syndrome.

In conclusion, considering that the ocular surface is a potential route of entry for the virus, if the results of this research were to be confirmed by studies on animal models and on humans, it would be conceivable to propose the topical administration of ozone-based ophthalmic gels to prevent the entry of SARS CoV-2 through the ocular surface.

The Director of the Gemelli Ophthalmology Unit believes that the ozone gel is “a protective measure to be recommended first of all to health professionals, and then to be extended to the entire population.”

Keep your eyes out for more on this topic. Medical ozone in several applications works. 

The scientific work was carried out by the researchers: Stanislao Rizzo, Maria Cristina Savastano, Alfonso Savastano, Gloria Gambini (Ophthalmology Unit, A. Gemelli IRCCS Polyclinic Foundation, Catholic University of the Sacred Heart); Daria Bortolotti, Valentina Gentili, Roberta Rizzo (University of Ferrara, Department of Chemical, Pharmaceutical and Agricultural Sciences); Francesca Caccuri (Department of Microbiology and Virology, Spedali Civili, Brescia).


Orbisphera editorial staff

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Can Antibiotics Cause Celiac Disease?

[fa icon="calendar'] Sep 2, 2021 12:48:45 PM / by Isadora Guggenheim posted in Autoimmune Disease, Gut Repair, Chronic Illness and Disease, Body Health

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Is there a connection? Researchers from the Karolinska Institute in Sweden think so because they found people with celiac disease were more likely to have used antibiotics in the year before their diagnosis.

Celiacs were more likely to have been prescribed multiple courses of antibiotics.

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ZONULIN and Degenerative Disease

[fa icon="calendar'] Aug 19, 2021 6:26:21 PM / by Dr. Isadora Guggenheim posted in Child and Teen Health, Men's Health, Detoxification, Autoimmune Disease, Gut Repair, Chronic Illness and Disease, Women's Health, Weight Loss and Obesity

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Plagues and infectious diseases that were previously the leading causes of death were largely eliminated with medical advances like vaccines and improvements in living conditions. Now, instead, we are plagued by chronic degenerative diseases. Several changes have occurred since the end of World War II that have contributed to the decline of our microbiomes and, from that, dysbiosis and the development of disease.

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[fa icon="calendar'] Aug 13, 2021 2:19:54 PM / by Dr. Isadora Guggenheim posted in Autoimmune Disease, Ozone and Prolozone therapies, Neurological Conditions, Chronic Illness and Disease

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Anyone who has faced a chronic disease wonders how they can rebuild their immune system. Whether it is Lyme, Cancer, autoimmune, chronic viral infections or poor detox pathways - one treatment modality to employ is I.V. Ozone which improves immune function, kills pathogens, down regulates inflammation and ignites all anti-oxidant pathways in all cells to prevent reactive oxygen species and cellular aging. 

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HASHIMOTO'S and I.V. Ozone

[fa icon="calendar'] Aug 4, 2021 9:01:31 AM / by Dr. Isadora Guggenheim posted in Autoimmune Disease, Gut Repair, Chronic Illness and Disease

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Hashimoto’s thyroiditis, also known as chronic autoimmune thyroiditis, is the most common autoimmune disease affecting the thyroid gland. When functioning properly, the thyroid gland produces hormones that regulate metabolism and other processes. With this disease, the thyroid is attacked by its own antibodies, leading to atrophy and decline in thyroid function. It affects women at a greater rate than men, possibly due to women’s low levels of androgens (i.e., testosterone), which protect against and treat autoimmune disorders. Often, cases of Hashimoto’s thyroiditis eventually progress to hypothyroidism.

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The Citric Acid Cycle

[fa icon="calendar'] Jul 12, 2021 8:35:04 AM / by Dr. Isadora Guggenheim posted in Detoxification, Allergies, Autoimmune Disease, Chronic Illness and Disease, Cancers

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Citric Acid Cycle Catalysts in Greater Detail

The contribution of homotoxicology to the progress of medicine has been pivotal because it links homeopathic concepts and laws to modern scientific knowledge. Dr. Reckeweg’s starting point was the study of homeopathic materia medica, but he enriched and added to it in various ways and on various levels.

Therapeutic approaches

"An original and essential contribution resulted from the great attention paid to the study of the cell, which Reckeweg defined as the primary and fundamental element in which disease originates.

An energy deficiency in the cell causes it to dysfunction, and an individual cell dysfunction is the start of a more complex pathology, which inevitably becomes an organic disorder.

When it enters a crisis, the cellular energy plant (i.e., the mitochondrion) begins to lack energy for any biochemical cellular process; in particular, the proteins, enzymes, and cytokines which are fundamental to the life of a specialized cell are not synthesized.

A cell that is lacking energy reduces its function to a minimum, uses large quantities of glucose via a metabolic route that does not require oxygen, pollutes the surrounding connective tissue, and progressively assumes the characteristics of a neoplastic cell.

This whole sequence of events which leads from normal physiology to dysfunction, to degeneration, and eventually to neoplasia, is initiated in the mitochondrion and, more specifically, in that sequence of oxidative reactions involved in pyruvic acid catabolism and ATP production.

It is clear how important it is to keep this sequence of key biochemical reactions as efficient as possible for both the catabolic and anabolic aspects of cell function. 

Patients with chronic degenerative diseases, which are those we encounter most frequently today in our natural medicine clinics, primarily need specific, selective stimulation of the citric acid cycle. Treatment with intermediary catalysts in a dilute, dynamized form offers an exceptional therapeutic opportunity in this domain.

The patient is assessed and, if this shows that he is in one of the cellular phases of the homotoxicology table, total stimulation of the citric acid cycle must be carried out, either by the administration of Coenzyme compositum or the individual catalysts if they are available.

If we consider that the organism often uses the building blocks of the citric acid cycle via many other metabolic pathways, it is clear that deficiencies of substances at various levels will tend to block the cycle once again. It is therefore useful to start therapy to support the citric acid cycle with Coenzyme compositum, at the rate of one ampoule sublingually or by injection 1 to 3 times weekly.

Children, in whom the citric acid cycle has presumably not reached a block as in adults or in chronically ill patients, can obviously start directly with the catalysts providing energy and a reactive stimulus to the organism. Although this is the best general strategy for using the citric acid cycle catalysts, it is also useful to be familiar with the role and consequently the clinical indications of the individual catalysts."


This is what I teach and practice. Pairing I.V. Ozone MAH with these German Biologics. We rebuild the immune system and repair damaged mitochondria to reverse chronic disease patterns.



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MELATONIN - You need it

[fa icon="calendar'] Jun 29, 2021 10:05:55 AM / by Dr. Isadora Guggenheim posted in Autoimmune Disease, Ozone and Prolozone therapies, Chronic Illness and Disease, Cancers, Corona Virus

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The Benefits of Melatonin

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Isadora Guggenheim, ND, FNP, RN, MS, CNS, LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963