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Vitamin E for Dementia - How Much do you Know? I.V. Ozone for Cognitive Issues

[fa icon="calendar'] Jul 25, 2017 5:00:00 AM / by Isadora Guggenheim

Vitamin E and it's positive prevention for dementia, how much do you know?

Vitamin E is an antioxidant important in the formation of red blood cells. It helps widen the vessels and keeps blood from clotting inside them. It can also have positive effects on the immune system, hair, skin and nails.

Although Vitamin E has not been found to prevent dementia in patients who already have a cognitive impairment; it did improve cognition. In observational studies, cognitive decline was correlated with decreased plasma selenium over time, and it is well known that high levels of selenium are toxic inducing a severe selenosis by pro-oxidant action and glial activation, leading to neuronal death. Vitamin E when used in an antioxidant cocktail failed to improve cognition in patients with AD with mild to moderate dementia. A study of dementia-asymptomatic older male patients, cited in an article published in JAMA Neurology,"investigated whether the supplements vitamin E and selenium used alone or in combination would prevent new [Alzheimer disease] or dementia onset. The results showed that neither vitamin E nor selenium had a significant preventive effect on incidence." Selenium appeared to elevate levels of type 2 diabetes, although this elevated rate subsequently decreased with additional follow up and that vitamin E appeared to increase prostate cancer incidence. The supplements had no effect on mortality, other cancers, cardiovascular events, nausea, fatigue, or nail changes. Selenium was associated with a significant increase in alopecia and in grades 1 and 2 dermatitis.

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1. True or False. Vitamin E has been found in trials to halt dementia progression in patients with mild cognitive impairment.

A. True
B. False

2. Which of the following statements is/are TRUE regarding selenium?

A. Cognitive decline is associated with plasma selenium levels decreasing over time
B. High selenium levels are toxic
C. A and B
D. None of the Above

3. True or False. According to study findings, vitamin E supplements improve cognition in patients with Alzheimer’s disease (AD) and mild dementia, when used in an antioxidant cocktail.

A. True
B. False

4. According to study findings, use of __________ supplements can prevent dementia onset in asymptomatic, older male patients.

A. Selenium
B. Vitamin E
C. A and B
D. None of the Above

5. Which of the following statements is FALSE regarding study findings of supplements?

A. Selenium elevates levels of type 2 diabetes
B. Selenium increases alopecia
C. Vitamin E increases prostate cancer incidence
D. Vitamin E increases mortality


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Answer Key:

1. B. False

2. C. A and B

3. B. False

4. D. None of the Above

5. D. Vitamin E increases mortality

For complete information, see:

Kryscio RJ, Abner EL, Caban-Holt A, et al. Association of antioxidant supplement use and dementia in the prevention of Alzheimer’s disease by vitamin E and selenium trial (PREADViSE). [Published online ahead of print March 20, 2017]. JAMA Neurol. Accessed April 11, 2017.

Topics: Neurological Conditions, Brain Health

Isadora Guggenheim

Written by Isadora Guggenheim

Isadora Guggenheim, ND, RN, MS, CNS LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963