Second Nature Care Blog

What does Gum Disease have to do with RA? - Curcumin, Prolozone & I.V. Ozone

[fa icon="calendar'] Jul 17, 2018 6:58:29 AM / by Winter Ninivaggi


Researchers have found that increased levels of gum-disease and disease causing bacteria increase the risk of rheumatoid arthritis.

RA is a chronic inflammatory disease that affects a person's joints, causing pain and disability. It can effect internal organs also. While it is typically more common in older people there is also a high prevalence in young adults, adolescents and even children. It also tends to affect more women than men.

The prevalence of gum disease is increased in patients with RA and could be a key initiator of RA-related autoimmunity. "This is because autoimmunity in RA is characterized by an antibody response to citrullinated proteins and the oral bacterium Porphyromonas gingivalis (Pg) is the only human pathogen known to express an enzyme that can generate citrullinated proteins."

This data enhances the clinical understanding of key initiators of RA.  "It has been shown that RA-associated antibodies, such as anti-citrullinated protein antibodies, are present well before any evidence of joint disease. This suggests they originate from a site outside of the joints," said Dr Kulveer Mankia of Leeds Institute of Rheumatic and Muscoskeletal Medicine and the Leeds Biomedical Research Centre (study author). "Our study is the first to describe clinical periodontal disease and the relative abundance of periodontal bacteria in these at-risk individuals. Our results support the hypothesis that local inflammation at mucosal surfaces, such as the gums in this case, may provide the primary trigger for the systemic autoimmunity seen in RA."

RA is difficult to treat beyond symptom control, it is possible to slow down the progression of joint damage if caught early enough. Generally conventional treatment just covers up the problem without healing it.

If RA goes untreated, patients can see permanent disability in as little as 3 years. The body tricks itself into fighting its own tissues in RA. Intestinal permeability or "leaky gut" plays a role in this disease as well. I recommend Megaspore probiotics to treat gut dysbiosis.

Turmeric is already known to relieve symptoms of RA and curcumin is the active ingredient in turmeric. It could be an herbal force in fighting RA.  In a study that tested the effects of curcumin on RA patients it out performed other botanicals for best results in symptom reduction.

At Second Nature we have safe and more effective treatments than the standard first-line therapy of Methotrexate.  Methotrexate is linked to lymphomas, T.B., malignant melanoma and other cancers with long-term use. We use natural anti-tumor necrosis factor agents, I.V. ozone, prolozone injections and natural anti- rheumatic homeopathics. We monitor your condition every 3 months with baseline labs. We don't just manage your condition we work to reverse it. All ozone treatments are MD/NP administered in NY.

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E. (n.d.). Gum disease may be a key initiator of rheumatoid arthritis related autoimmunity. Retrieved from

Topics: Chronic Illness and Disease

Winter Ninivaggi

Written by Winter Ninivaggi

Isadora Guggenheim, ND, RN, MS, CNS LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963