According to a recent study, patients suffering with chronic migraines had smaller midbrain volumes and significant inward deformations in the ventral midbrain and pons and outward deformations in the lateral medulla and dorsolateral pons relative to healthy controls. Migraineurs with greater symptoms of allodynia have smaller midbrain volumes. Study analysis found a significant negative correlation between allodynia and midbrain volume in migraineurs suggesting that more severe symptoms of allodynia were related to less midbrain volume. In patients with migraine, cutaneous allodynia can persist through both ictal and interictal periods. According to study findings, patients with migraine without aura had greater cerebellar and brainstem density compared to healthy controls. “Migraineurs with lower heat pain thresholds have smaller medulla and cerebellar peduncles,” according to study findings cited in an article published in NeuroImage: Clinical, where “there was a significant positive correlation between cutaneous heat pain thresholds and medulla and cerebellar peduncle volume indicating that migraine patients who were more sensitive to heat pain had less cerebellar peduncle and medulla volume.”
1. Compared to healthy controls in study findings, patients with migraine had __________.
B. Inward deformations in the ventral midbrain and pons
C. Outward deformations in the lateral medulla and dorsolateral pons
D. B and C
2. True or False. In patients with migraine, cutaneous allodynia can persist through both ictal and interictal periods.
3. According to study findings of patients with migraine, decreased midbrain volume was associated with __________ severe allodynia symptoms.
4. True or False. According to study findings, patients with migraine without aura had greater cerebellar and brainstem density compared to healthy controls.
At Second Nature we look at a person's history as a whole. You are not just a chart that gets passed around. You are an individual and we take into account many aspects of your life, such as your history, background, and lifestyle to help find the best options for you. If you suffer from migraines, naturopathic medicine offers many safe options such as safe and effective Ozone therapy, melatonin and medicinal marijuana. All I.V. therapies are MD supervised and RN/NP administered in NY.
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1. D. B and C
2. A. True
3. A. More
4. B. False
5. B. Lesser
For complete information, see:
Chong CD, Plasencia JD, Frakes DH, Schwedt TJ. Structural alterations of the brainstem in migraine. Neuroimage Clin. 2017;13:223-227.