How does a stroke affect the gut?
Scientists from the West Virginia University School of Medicine revealed distinct changes are observed in an animal's gut (microbiome) after suffering an induced stroke. The alterations were persistent for several weeks following the stroke adding compelling new evidence to the Gut-Brain connection.
Prior research has revealed that a stroke has an immediate impact on the microbiome but, how long the effects lasted was unknown. Several key bacterial shifts were prominently identified in the days following a stroke. A notable decrease was seen in Bifidobacteriaceae, a common bacteria found in probiotics, up to four weeks post stroke, while increases were seen in Helicobacteraceae across the same observational period.
Another big post-stroke change was seen in the ratio of Firmicutes-to-Bacteriodetes. An imbalance in the ratio between these two bacteria has been implicated in a variety of metabolic disorders, including diabetes and obesity. Two weeks after the stroke this ratio was six times higher than the control group. At the four-week point post-stroke the ratio had fallen and was still three times higher than normal. (Haridy, 2019)
"Big picture: seeing a persistent, chronic change 28 days after stroke that is associated with this increase in some of the negative bacteria means that this could have negative effects on brain function and behavior," says Candice Brown, one of the researchers working on the project. "Ultimately, this could slow or prevent post-stroke recovery." (Haridy 2019)
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Haridy, R. (2019, March 13). The fascinating effect a stroke has on the gut microbiome. Retrieved from https://newatlas.com/microbiome-stroke-gut-bacteria-brain/58836/