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Associations between Primary Biliary Cholangitis and Thyroid Disease - I.V. Ozone

Written by Isadora Guggenheim | Apr 8, 2017 9:00:00 AM

 

 

Associations are known to exist between primary biliary cholangitis (autoimmune disease that causes progressive destruction of the bile ducts) and many different types of thyroid disease.  Researchers recently aimed to determine if the presence of thyroid disease has any impact on hepatic complications or progression of PBC. Among patients with PBC the most common in TD patients was Hashimoto's thyroiditis. In a recent study, patients also had graves disease and multinodular goiter. The study found no significant differences in PBC patients who had TD and those who did not, when it came to comparing the histologic stages at which they were diagnosed with PBC. The researchers found no significant differences between patients with PBC who had TD and those who did not regarding hepatic decompensation events, occurrence of hepatocellular carcinoma, or liver transplantation rate. TD was not found to affect PBC survival rates, either positively or negatively.

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1. True or False. There are known associations between primary biliary cholangitis and different types of thyroid disease.

A. True
B. False

2. Findings from a prospective study of PBC patients showed that the most common thyroid disease among those with PBC was _______________.

A. Graves’ disease
B. Hashimoto’s thyroiditis
C. Thyroid cancer
 
3. True or False. Significant differences were found in histologic stages at diagnosis between patients with PBC who had TD and patients who did not.
 
A. True
B. False

 

4. In this same study, researchers found _______________ between patients with PBC who had TD and those who did not regarding hepatic decompensation events, occurrence of hepatocellular carcinoma, or liver transplantation rate.

A. Significant differences
B. No significant differences

 

5. Findings from this research showed that TD __________________ PBC survival rates.

A. Positively effected
B. Negatively effected
C. Did not effect

Answer Key:

1. A. True

2. B. Hashimoto's thyroiditis

3. B. False

4. B. No significant differences

5. C. Did not effect