Correlation between psoriasis and major depressive disorder and psoriatic arthritis.
Patients with a diagnosis of both psoriasis and major depressive disorder face about a 37% higher risk of developing psoriatic arthritis over a median follow up of 5.1 years.
Although the correlation does not prove causality, efforts should be made to identify and address depression in patients with psoriasis. Researchers have also linked psoriasis with a higher risk of depression. One study found patients with psoriasis had twice the odds of developing major depression.
The median age at psoriasis diagnosis was 49.5 years (range, 20-90 years) and the median follow-up time was 5.1 years; 2% of the patients developed PsA and 7% developed major depression.
Those with signs of depression were 1.56 times more likely to develop psoriatic arthritis. Although the biological methods by which depression increases the risk of psoriatic arthritis, depression is known to be linked to poor diet and lack of exercise which are also factors in increasing the risk of developing psoriatic arthritis.
If you are living with depression, psoriasis or psoriatic arthritis or all three, there are safe and effective treatment options.
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