Conclusive evidence to show the benefits of using I.V. Ozone therapy with a stroke patient.
Chronic Lyme Disease and Co-Infections.
OZONE THERAPY TO TREAT COGNITIVE FRAGILITY
Is it possible to cure the condition of cognitive fragility which, in increasing percentages, affects the elderly population with a non-pharmacological therapy, at low cost, without side effects?“The answer is yes”. According to doctors and professors Catia Scassellati et al, it is possible to answer this question in the affirmative.The solution is in the practice of oxygen ozone therapy, which is able to “modulate the immune, inflammatory, oxidant, metabolic, endocrine, microbiotic and regenerative processes altered in cognitive fragility” and which “could represent a convenient and economical single intervention, functioning in the absence of side effects”.Their solution was illustrated in a well-documented study published by the journal Mechanisms of Aging and Development.The study cited explains that, in the last decade, cognitive fragility has gained great attention from the scientific community. Although several treatments are available, problems persist regarding both the effectiveness and costs of treatment.For this reason, the authors of the study propose oxygen ozone therapy which, in an economical and efficient way, could modulate the immune, inflammatory, oxidizing, metabolic, endocrine, microbiota and regenerative processes compromised in cognitive fragility.Positive Effects of Ozone TherapyThe positive effects of ozone are mainly attributed to the activation of the immune and anti-inflammatory systems, to the upregulation of cellular antioxidant enzyme activity, to the improvement of the release of growth factors from platelets, to enhanced blood circulation and to the the consequent better delivery of O2 to the tissues. This leads to an enhanced overall metabolism.The study emphasizes that oxygen-ozone therapy “acquires significant value due to its well-known and widely demonstrated ability to cure a broad spectrum of diseases: cardiovascular (coronary artery disease); metabolic (diabetes, hyperglycemia); respiratory (emphysema, chronic obstructive pulmonary disease); neurodegenerative (Alzheimer’s disease and Parkinson’s disease); digestive disease (steatosis, non-alcoholic steatohepatitis, cirrhosis)”.An increasing number of clinical studies have highlighted the efficacy of oxygen ozone therapy in the treatment of cardiovascular, peripheral vascular, neurological, degenerative, orthopedic, gastrointestinal and genitourinary diseases, as well as in the treatment of multiple sclerosis, fibromyalgia, skin diseases, wounds, ulcers from diabetes, infectious diseases, lung diseases, osteomyelitis.Citing the huge bibliography available, the authors emphasize that “oxygen ozone therapy is a non-invasive, non-pharmacological and side-effect-free procedure applied in medicine for the treatment of over 50 different diseases”.In this regard, the authors of the study recall that in 2016 the Italian Ministry of Health approved a project (RF 2016-02363298) aimed at testing the effectiveness of oxygen ozone therapy in the treatment of cognitive fragility.The authors conclude by stating that “while being aware that further studies are needed, this review reports substantial scientific evidence to build a rationale for the use of oxygen ozone therapy in an early stage of cognitive decline, when it is still possible to intervene before a potential neurodegenerative pathology”.To date, cognitive frailty is considered a geriatric condition characterized by the coexistence of a condition of physical frailty with a specific degree of cognitive impairment.In 2006, “cognitive fragility” was indicated as a clinical label for a particular vulnerable state in mild cognitive impairment (MCI) and other similar clinical entities exposed to vascular risk factors, resulting in increased progression to dementia.Since 2007, frailty has also been considered in its biological and psychosocial aspects. In this case, the frailty index represents a measure of the general decline in health associated with age, due to the accumulation of health-related deficits.In 2013 a common consensus was reached on the definition of “cognitive frailty” thanks to the International Academy of Nutrition and Aging (IANA) and the International Association of Gerontology and Geriatrics (IAGG).The authors of the study are all Italian. Doctors Scassellati, Ciani, Zanardini, Bonvicini and Geroldi work and teach at the Biological Psychiatry Unit, Molecular Marker Laboratory, Alzheimer Unit of the IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli in Brescia. Dr. Galoforo, among his many professional positions, is a member of the board of the SIOOT (Scientific Society of Oxygen Ozone Therapy) and lecturer at the Master in Ozone Therapy at the University of Pavia.“Molecular mechanisms in cognitive frailty: potential therapeutic targets for oxygen-ozone treatment”Journal: Mechanisms of Aging and DevelopmentCatia Scassellati, Miriam Ciani, Antonio Carlo Galoforo, Roberta Zanardini, Cristian Bonvicini, Cristina GeroldiFULL TEXT:Antonio GaspariDirector Orbisphera
Peptide therapy is an evolving, cutting edge, medical science in which specific, bio-identical, protein amino acid sequences called "peptides" are used to repair, regenerate, support and improve the structure and function of different parts of the mind and body.
Ozone is not some kooky idea from outer space. It has been used in over 71 clinical trials during the pandemic. Below is a summary of several studies from a leading journalist in Italy. I enclose his contact information so the public can address him directly.
Ozone Disinfection Could Safely Allow Reuse of Personal Protective Equipment
"The O2-O3 therapy is a non-invasive, non-pharmacological, no-side effect and low-cost procedure applied in medicine for the treatment of more than 50 pathological processes, whose alterations in endogenous oxidative-antioxidative balance play a crucial role . Different clinical trials evidenced the effectiveness of this therapy in the treatment of degenerative disorders such as multiple sclerosis (Smith et al., 2017, Delgado-Roche et al., 2017, Ameli et al., 2019), but also cardiovascular, peripheral vascular, neurological, orthopedic, gastrointestinal and genitourinary pathologies (Bocci, 2011, Elvis, Ekta, 2011, Re et al., 2008, Bocci, 2012, Smith et al., 2017, Braidy et al., 2018); fibromyalgia (Moreno -Fernandez et al., 2019, Tirelli et al., 2019); skin diseases / wound healing (Fitzpatrick et al., 2018, Wang, 2018); diabetes / ulcers (Martinez-Sanchez et al., 2005, Guclu et al. ., 2016, Rosul, Patskan, 2016, Izadi et al., 2019, Ramirez-Acuna et al., 2019); infectious diseases (Smith et al., 2017, Mandhare et al., 2012, Song et al., 2018), including the recent global pandemic disease of coronavirus disease 2019 (COVID-19) (Zheng et al., 2020); dentistry (Isler et al., 2018, Khatri et al., 2015, Srikanth et al., 2013, Azarpazhooh et al., 2009); lung diseases (Hernandez Rosales et al., 2005); osteomyelitis (Bilge et al., 2018). The potential role of O2-O3 as an adjuvant therapy for cancer treatment has been also suggested in in vitro and animal studies as well as in isolated clinical reports (Clavo et al., 2018).
At present, we have commenced a randomized double-blind clinical trial with the aim to test the efficacy of this therapy in a cognitive frailty cohort, a grant approved by the Italian Minister of Health (RF-2016-02363298). This pilot study will permit to validate the O2-O3 therapy in an early phase of cognitive decline, when it is still possible to intervene, before to develop a potential neurodegenerative pathology.
To date, the O2-O3 therapy acquires a further prestigious significance, after the medicine Nobel prize for "discovery of how cells sense oxygen" in 2019. Indeed, O2 is the most vital element required for human life and it is the key to good health; O3 is O2 with an extra molecule added. The O2 availability affects genes expression of different factors (HIFs, Hypoxia Inducible Factors), leading to the activation of trophic proteins (VEGF, Vascular Endothelial Growth Factor; PDGF, Platelet-derived growth factor) and consequently to specific biological processes, including erythropoiesis, angiogenesis and anaerobic glucose metabolism (Zhou et al., 2019). O3 plays a role of cellular adapter to hypoxia, because it is well known its effects in increasing the levels of VEGF, PDGF, HIF (Curro et al., 2018, Zhang et al., 2014, Re et al., 2010), exactly as the cell does when there is no O2 available ".
A diagnosis of ADD/ADHD can have a parent desperately searching for the best and safest way to treat their child.
Chronic Lyme Disease and Co-Infections.