Second Nature Care Blog

Vitamin D Deficiency and Addictions I.V. Amino Acids

[fa icon="calendar'] Jul 26, 2021 9:28:55 AM / by Dr. Isadora Guggenheim

Scientists at Massachusetts General Hospital recently discovered a “strong link” between vitamin D levels and opioid addiction.

This follows a previous study that found people could become addicted to tanning because of UV light exposure triggering the production of a hormone called beta-endorphin. When UV light hits the skin, beta-endorphins begin production. Beta-endorphins are involved in the high after exercise, and other feelings. Scientists hypothesize that this adaptation helped our ancestors maintain constant sun exposure, which helps vitamin D production, and rewarded them with good health.

We test all patients for converted and unconverted Vitamin D3. We offer I.V. therapies and oral protocols to address insufficiencies and deficiencies. 


Scientists found a similar response to opioids in those with low vitamin D levels. After regularly receiving morphine, mice deficient in vitamin D experienced more “drug-seeking and addictive behaviors” and greater symptoms of withdrawal than those with normal vitamin D levels. These behaviors returned to normal when their vitamin D levels were brought up to normal levels. People with opioid use disorder (OUD) were also found to be more likely to have this deficiency.

Researchers hope this discovery can open a new door in addiction prevention and treatment. Vitamin D supplementation could be used to lower chances of opioid addiction with vulnerable, deficient people.

Vitamin D deficiency and genomic polymorphisms combine to create the perfect storm for addictions. 


Haridy, R. (2021, June 14). Vitamin D deficiency linked to opioid addiction. New Atlas.

Topics: Detoxification, Ozone and Prolozone therapies, Neurological Conditions, Brain Health, Mental Health

Isadora Guggenheim, ND, FNP, RN, MS, CNS, LMT, owner of Second Nature Naturopathic Care, LLC
For all appointments: Tel: 845 358-8385 Fax: 845 358-2963