Many patients with chronic Lyme or other inflammatory autoimmune conditions have Mast Cell Activation Syndrome or MCAS. Many environmental insults contribute to MCAS and serve as triggers for lighting the fire within. Mast cells become activated and rupture releasing histamines into tissues and the bloodstream. This in turn creates inflammation in the body and abnormal immune responses. In order to address the other headlined condition - Lyme, inflammatory arthritis, Hashimoto's, sarcoidosis and such the fire must be put out first.
What is a mast cell? Mast cells are white blood cells that are formed from your bone marrow. They contain basophilic granules that release inflammatory chemical messenger proteins, histamine and other chemicals that sound the alarm when your body encounters parasites, medications, infections, stress, spirochetes, food allergies, toxic mold, environmental contaminants and other pathogens.
Mast cells are part of our immune system and they are found in connective tissue, epithelial lining of the gastrointestinal tract and the lungs. They balance inflammation in our blood vessels. This is of interest because of "cytokine storm" in the news with Covid-19. Patients are dying of overwhelming inflammatory responses and hypoxia or lack of oxygen.
MCAS is an excessive release of histamines and it can affect every organ system in the body. MCAS is a co-morbidity condition that accompanies several chronic diseases. MCAS expression can present with hives, rashes, flushing, itching, abdominal pain, bloat and distention, reflux, nausea, diarrhea, low blood pressure or hypotonia, heart palpitations, headaches, brain fog, anxiety, fatigue, shortness of breath, muscle weakness, dizziness, osteoporosis and mood disorders.
MCAS is seen as the immune system going haywire. The immune system goes into unregulated dysfunction where Th1 immunity is inhibited and we move towards a Th2 response with more allergic inflammation is experienced.
"Mast cell comes from the German word mastzellen which means fattening." German immunologist Paul Ehrlich originally thought mast cells were nourishing.
What triggers mast cell activation?
Lyme and tick borne infections, mold toxicity, heavy metals, EMF's/5G, viruses, pneumonias, medications, supplements, high histamine foods, temperature changes, physical, mental or emotional stress and traumas of all kinds. Once you read this list - you may feel like well everything causes mast cell activation. You're right. Treatment protocols must be done carefully because even quick detoxification can cause disruption. Low and slow to get to goal.
How do you test for MCAS?
There are some tests that can help to identify this syndrome
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https://www.zerohedge.com/geopolitical/smith-why-public-should-rebel-against-forced-vaccinations
https://www.jpost.com/health-science/made-in-israel-anti-pathogen-mask-registered-for-marketing-by-fda-629241https://www.downtoearth.org.in/news/health/the-vaccinegate-of-italy-63235%MCEPASTEBIN%