How much do you know about MS?
According to a recent study, cognitive impairment at the time of multiple sclerosis diagnosis "imparts a significantly higher risk for disability progression, transition to secondary progressive disease, and cortical thinning." The results from the study identified cortical thinning as a neuroimaging correlate of cognitive impairment that was detected only at follow-up between the cognitively impaired and cognitively normal patients. "Patients with relapsing-remitting MS with severe cognitive impairment at baseline had more severe white matter lesion volume at baseline than did others but, there was no difference in the accumulation of white matter lesions during follow-up between patients with normal cognition, mild cognitive impairment, and severe cognitive impairment which corroborates previous studies.” Of the cognitively normal patients, 15% had disability progression. Several previous studies have demonstrated a strong relationship between gray matter damage and cognitive impairment.
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